Education
- 2023: Master in Gestione Clinica delle Cardiomiopatie, University of Trieste, Italy
- 2022: AIFA Phase I clinical trials certification
- 2017 – 2021: PhD in Molecular and Experimental Medicine, Humanitas University, Milan, Italy
- 2012 – 2017: Cardiologist Specialist (grade 60/60 cum laude), University of Florence
- 2005 – 2011: Doctor of Medicine (grade 110/110 cum laude), University of Milan, Italy
- 1999 – 2004: Humanistic Studies High School, Liceo “classico” L. Costa, La Spezia, Italy
Academic Appointments
- 2023 – present: RTD-A, Humanitas University
- 2023 – present: Assistant Professor, Humanitas University
Awards and Honors
- 2020 – 2023: Humanitas Research Hospital Grant (5×1000 Funding). Development of Machine Learning-based diagnostics to guide diagnosis of Heart Failure with Preserved Ejection Fraction. EUR 98’000. Role: Principal Investigator
- 2020 – 2023: 2019 Targeted research call. Immunophenotyping in human heart failure: clinical correlations for potential therapeutic indications. EUR 450,000. Role: Co-PI
- 2019 – 2022: Humanitas Research Hospital Grant (5×1000 Funding). Correlation between clinical and immune phenotypes in Chronic Heart Failure (Immuno-heart). EUR 72’000. Role: Principal Investigator
Dr. Cristina Panico is currently a Researcher at Humanitas University. In January 2017, Dr Panico has been selected as Research Fellow for a translational research programme in Cardiology evaluating cardiac-derived macrovesicles as novel biomarkers for cardiovascular diseases. In June 2021 she obtained the PhD of Molecular and Experimental Medicine PhD course at Humanitas University and Hospital, Rozzano-Milan, Italy, working on a translational project regarding inflammation and heart failure with preserved ejection fraction, which includes the development of a new mice model, gene expression and epigenetic modulation of the cells involved. She currently coordinates the cardiovascular pharmacological clinical trial unit and she is local-PI of several phase I-IV clinical trials prospective registries. She is collaborating in translational projects regarding cancer and immune system involvement in cardiovascular diseases. She also is in charge of the family cardiomyopathies and dyslipidemias program. She has presented different oral communications at major cardiovascular congresses, has authored 21 peer-reviewed articles. She acts as reviewer for the peer-reviewed journals
- Panico C, Felicetta A, Kunderfranco P, et al. Single-Cell RNA Sequencing Reveals Metabolic Stress-Dependent Activation of Cardiac Macrophages in a Model of Dyslipidemia-Induced Diastolic Dysfunction. Circulation. 2023 Dec 21. doi: 10.1161/CIRCULATIONAHA.122.062984. Epub ahead of print. PMID: 38126199.
- Martini E, Kunderfranco P, Peano C, Carullo P, Cremonesi M, Schorn T, Carriero R, Termanini A, Colombo FS7, Jachetti E, Panico C, Faggian G, Fumero A, Torracca L, Molgora M, Cibella J, Pagiatakis C, Brummelman J, Alvisi G, Mazza EMC, Colombo MP, Lugli E, Condorelli G, Kallikourdis M. Single-Cell Sequencing of Mouse Heart Immune Infiltrate in Pressure Overload-Driven Heart Failure Reveals Extent of Immune Activation. Circulation. 2019 Dec 17;140(25):2089-2107. doi: 10.1161/CIRCULATIONAHA.119.041694. Epub 2019 Oct 30.
- Cremonesi M, Felicetta A, Cannata F, Panico C. et al. Long COVID-19 Cardiac Complications Are Associated With Autoimmunity to Cardiac Self-Antigens Sufficient to Cause Cardiac Dysfunction. Circulation. 2023;148(6):504-507. doi:10.1161/CIRCULATIONAHA.122.062672
- Martini, E., Cremonesi, M., Panico, C., Carullo, P., Bonfiglio, C.A., Serio, S., Jachetti, E., Colombo, M.P., Condorelli, G., Kallikourdis, M. T Cell Costimulation Blockade Blunts Age-Related Heart Failure (2020) Circulation Research, pp. 1115-1117.
- Panico C, Bonora B, Camera A, et al. Pathophysiological basis of the cardiological benefits of SGLT-2 inhibitors: a narrative review. Cardiovasc Diabetol. 2023;22(1):164. doi:10.1186/s12933-023-01855-y3