- 1994 he graduated with his MD degree in Medicine and Surgery from the University of Rome, La Sapienza
- 1999 he went on to complete post-graduate study and received a speciality degree in Internal Medicine
- 2006 Dermatology speciality degree.
In our group we study the molecular mechanism at the basis of immune-mediated cutaneous disease as Psoriasis, a chronic inflammatory, hyperproliferative skin disease, using the approach of epigenetic analysis (ChIP seq) and gene regulation technics to map key genes responsible of the onset of the skin hyperproliferation, and to highlight the genes that respond to the different drug therapy. We are interested in Pharmacogenetic, to correlate the response of biological drugs to the different haplotypes. INNODERM project focus on the development of an Innovative Dermatology Healthcare based on Label-Free Spectral Optoacoustic Mesoscopy.
- IL12B (p40) Gene Polymorphisms Contribute to Ustekinumab Response Prediction in Psoriasis.Galluzzo M1, Boca AN, Botti E, Potenza C, Malara G, Malagoli P, Vesa S, Chimenti S, Buzoianu AD, Talamonti M, Costanzo A., Dermatology. 2016;232(2):230-6. doi: 10.1159/000441719. Epub 2015 Dec 18., https://www.karger.com/Article/FullText/441719
- Use of biological drugs in patients with psoriasis and psoriatic arthritis in Italy: Results from the PSONG survey. Potenza MC, Peris K, Berardesca E, Bianchi L, Richetta A, Bernardini N, De Simone C, Teoli M, Zangrilli A, D’epiro S, Orsini D, Narcisi A, Chimenti S, Costanzo A., Dermatol Ther. 2018 Jan;31(1). doi: 10.1111/dth.12565. Epub 2017 Dec 7., https://onlinelibrary.wiley.com/doi/epdf/10.1111/dth.12565
- The antimicrobial peptide LL37 is a T-cell autoantigen in psoriasis., Lande R, Botti E, Jandus C, Dojcinovic D, Fanelli G, Conrad C, Chamilos G, Feldmeyer L, Marinari B, Chon S, Vence L, Riccieri V, Guillaume P, Navarini AA, Romero P, Costanzo A, Piccolella E, Gilliet M, Frasca L., Nat Commun. 2014 Dec 3;5:5621. doi: 10.1038/ncomms6621., https://www.nature.com/articles/ncomms6621
- Disease-related and drug-induced skin manifestations in inflammatory bowel disease., Hindryckx P, Novak G, Costanzo A, Danese S., Expert Rev Gastroenterol Hepatol. 2017 Mar;11(3):203-214. doi: 10.1080/17474124.2017.1283985. Epub 2017 Feb , https://www.tandfonline.com/doi/abs/10.1080/17474124.2017.1283985?journalCode=ierh20
- Listening in to skin disease Optoacoustic mesoscopy promises to be a fast and reliable non-invasive method for the diagnosis of psoriasis. Narcisi A, Favaro R. Costanzo A., Nature Biomedical Engineering 1, 0076 (2017) | DOI: 10.1038/s41551-017-0076, https://www.nature.com/articles/s41551-017-0076.pdf?origin=ppub