Education
- 2006: Specialisation in Dermatology
- 1999: Specialisation in Internal Medicine
- 1994: Degree in Medicine and Surgery from the University of Rome, La Sapienza
Research into the molecular mechanisms underlying immune-mediated skin diseases, with a particular focus on psoriasis, a chronic inflammatory and hyperproliferative disease. Study of epigenetic approaches (ChIP-seq) and gene regulation techniques to map the key genes responsible for skin hyperproliferation and identify those that respond to different drug therapies. Interest in pharmacogenetics to correlate response to biological drugs with specific haplotypes. The INNODERM project focuses on the development of innovative dermatological tools based on spectral optoacoustic mesoscopy.
- IL12B (p40) Gene Polymorphisms Contribute to Ustekinumab Response Prediction in Psoriasis.Galluzzo M1, Boca AN, Botti E, Potenza C, Malara G, Malagoli P, Vesa S, Chimenti S, Buzoianu AD, Talamonti M, Costanzo A., Dermatology. 2016;232(2):230-6. doi: 10.1159/000441719. Epub 2015 Dec 18.
- Use of biological drugs in patients with psoriasis and psoriatic arthritis in Italy: Results from the PSONG survey. Potenza MC, Peris K, Berardesca E, Bianchi L, Richetta A, Bernardini N, De Simone C, Teoli M, Zangrilli A, D’epiro S, Orsini D, Narcisi A, Chimenti S, Costanzo A., Dermatol Ther. 2018 Jan;31(1). doi: 10.1111/dth.12565. Epub 2017 Dec 7.
- The antimicrobial peptide LL37 is a T-cell autoantigen in psoriasis., Lande R, Botti E, Jandus C, Dojcinovic D, Fanelli G, Conrad C, Chamilos G, Feldmeyer L, Marinari B, Chon S, Vence L, Riccieri V, Guillaume P, Navarini AA, Romero P, Costanzo A, Piccolella E, Gilliet M, Frasca L., Nat Commun. 2014 Dec 3;5:5621. doi: 10.1038/ncomms6621.
- Disease-related and drug-induced skin manifestations in inflammatory bowel disease., Hindryckx P, Novak G, Costanzo A, Danese S., Expert Rev Gastroenterol Hepatol. 2017 Mar;11(3):203-214. doi: 10.1080/17474124.2017.1283985. Epub 2017 Feb
- Listening in to skin disease Optoacoustic mesoscopy promises to be a fast and reliable non-invasive method for the diagnosis of psoriasis. Narcisi A, Favaro R. Costanzo A., Nature Biomedical Engineering 1, 0076 (2017) | DOI: 10.1038/s41551-017-0076