Sara Carloni obtained her Ph.D. in Biological and Molecular Sciences at Microbiology Unit of the University of Milan. During her Ph.D. training she investigated sRNAs-based molecular mechanisms regulating the host pathogen interaction and virulence of Pseudomonas aeruginosa.
She then joined the group of Prof. Maria Rescigno as Post Doc, at the European Institute of Oncology where she investigated the involvement of bacteria isolated from clinical and preclinical cancer models in tumorigenesis and metastatization.
Since January 2018, she is member of Mucosal immunology and Microbiota Unit of Prof.ssa Rescigno at Humanitas University.
Academic honors, awards and prices
- Winner of the best preclinical Research Poster – Humanitas Research Hospital
- Identification of a Choroid Plexus Vascular Barrier which closes up during intestinal inflammation leads to behavioral impairments (2029)
- Role of Gut Vascular Barrier (GVB) in maintaining mucosal immunity response and Microbiota homeostasis of gut-liver-brain axis in Intestinal Bowel Diseases
- Isolation and Characterization of intestinal and intra-tumoral bacteria for pathogenicity, antibiotic resistance, biofilm formation and tumorigenesis
- Characterization of pro- and anti-tumorigenic microbiota isolated from clinical and preclinical
- Zagato E., Pozzi C., Bertocchi A., Schioppa T., Saccheri F., Guglietta S., Fosso B., Melocchi L., Nizzoli G., Troisi J., Marzano M., Oresta B., Spadoni I., Atarashi k., Carloni S., Airoli S., Fornasa G., Asnicar F., Segata N., Guglielmetti S., Honda k., Pesole G., Vermi W., Penna G., Rescigno M. Endogenous murine microbiota member Faecalibaculum rodentium and its human homologue protect from intestinal tumor growth. Nature Microbiology-2020 https://doi.org/10.1038/s41564-019-0649-5
- C. Burrello, F. Garavaglia, F. Milena Cribiù, G. Ercoli, S. Guglietta, S. Carloni, S. Guglielmetti, V. Taverniti, G. Nizzoli, S. Bosari, F. Caprioli, M. Rescigno, F. Facciotti. Therapeutic faecal microbiota transplantation controls intestinal inflammation through IL10 secretion by immune cells, Nature Communications-2018. https://doi.org/10.1038/s41467-018-07359-8 – 2018
- Sara Carloni, Raffaella Macchi, Sara Sattin, Silvia Ferrara, Giovanni Bertoni. The small RNA ReaL: a novel regulatory element embedded in the P. aeruginosa quorum sensing networks. Environmental Microbiology, 2017. https://doi.org/10.1111/1462-2920.13886
- Silvia Ferrara, Sara Carloni, Roberta Fulco, Marilena Falcone, Giovanni Bertoni. Post-transcriptional regulation of the virulence-associated enzyme AlgC by the sigma-dependent small RNA ErsA of Pseudomonas aeruginosa. Environmental Microbiology-2014. https://doi.org/10.1111/1462-2920.12590