Education
- 2015 – 2019: PhD degree in Medical Physics, Aarhus University
- 2004 – 2008: Postgraduate degree in Medical Physics, University of the Study of Milano
- 1999 – 2004: Master Degree in Physics, University of the Study of Milano
Academic Appointments
- 2025 – present: Associate Professor Physics for Life Sciences (PHYS-06/A), Humanitas University
- 2024 – present: Honorary professor, Department Medical Physics and Biomedical Engineering, University College London (UCL)
Awards and Honors
- 2021: Award for the best Lean project in the ‘New Areas’ category at the 2021 Italian Lean Healthcare Awards (DOI: 10.1002/mp.14783)
- 2017: Galileo Galilei Award for the best article published in Physica Medica in 2016 (DOI: 10.1016/j.ejmp.2015.09.009)
- 2012: Principal investigator of the study awarded the highest score among the technical abstracts presented at ESTRO 31 (DOI: 10.1118/1.4823767)
- 2008: Il Grifo d’Oro Award – ISPESL category, for the best Master’s thesis in Medical Physics (DOI:10.1016/j.radonc.2008.04.007)
The main research interests are:
- Automation and artificial intelligence in radiotherapy, with particular focus on quality assurance and treatment planning optimization
- Physics of stereotactic body radiation therapy (SBRT)
- Physics of total marrow irradiation (TMI) in hematologic malignancies
- Risk management and failure mode and effects analysis (FMEA) in radiotherapy
- Proton therapy physics
He has served as Associate Editor of the Journal of Applied Clinical Medical Physics (since 2011), Physica Medica (since 2016), and Physics and Imaging in Radiation Oncology (since 2023). He has been a member of the working group of the Italian National Institute of Health (Istituto Superiore di Sanità) on quality and safety in radiotherapy since 2023, contributing to the development of recommendations in this field. He is a member of ESTRO, EFOMP, and AIFM. Within ESTRO, he contributed to the drafting of the guidelines on spinal SBRT (2023–2024), coordinates the technical guidelines on SBRT (2025–2026), and has been a member of the ESTRO School for Image-Guided Stereotactic Body Radiation Therapy since 2024.
Within AIFM, he is coordinator of the Italian working group on SBRT physics and dosimetry, a member of the Scientific Committee (since 2018), and AIFM representative to ESTRO (since 2019). Since 2008, he has been Medical Physicist at the Department of Radiotherapy and Radiosurgery, IRCCS Humanitas Research Hospital, Rozzano, Italy. He is the author of more than 180 publications in international journals in the field of physics applied to medicine. 2008
- Lambri N, […], Mancosu P. Deep learning-based optimization of field geometry for total marrow irradiation delivered with volumetric modulated arc therapy.. Med Phys. 2024 Jun;51(6):4402-4412. doi: 10.1002/mp.17089.
- Hardcastle N, […], Mancosu P. Recommendation on the technical and dosimetric data to be included in stereotactic body radiation therapy clinical trial publications based on a systematic review.. Radiother Oncol. 2024;190:110042. doi: 10.1016/j.radonc.2023.110042.
- Mancosu P, et al. Applications of artificial intelligence in stereotactic body radiation therapy. Phys Med Biol. 2022;67(16). doi: 10.1088/1361-6560/ac7e18
- Wong JYC, Filippi AR, Scorsetti M, Hui S, Muren LP, Mancosu P. Total marrow and total lymphoid irradiation in bone marrow transplantation for acute leukaemia. Lancet Oncol. 2020 Oct;21(10):e477-e487. doi: 10.1016/S1470-2045(20)30342-9.
- Mancosu P, et al. Applying Lean-Six-Sigma Methodology in radiotherapy: Lessons learned by the breast daily repositioning case. Radiother Oncol. 2018 May;127(2):326-331. doi: 10.1016/j.radonc.2018.02.019.