Academic Background and Education
- 2022 – 2024: Researcher (RTD-B) in Diseases of Locomotor Apparatus Disease and Physical and Rehabilitative Medicine, Humanitas University, Pieve Emanuele (Milan, Italy)
- 2022: Scientific National Abilitation for Full Professor of Locomotor Apparatus Disease and Physical and Rehabilitative Medicine
- 2017 – 2022: Researcher (RTD-A) in Diseases of Locomotor Apparatus Disease and Physical and Rehabilitative Medicine, Humanitas University, Pieve Emanuele (Milan, Italy)
- 2018: Scientific National Abilitation for Associate Professor of Locomotor Apparatus Disease and Physical and Rehabilitative Medicine
- 2016 – 2017: Advanced Training Course in Clinical Epidemiology, Humanitas University, Rozzano, Milan, Italy.
- 2012 – 2015: PhD program in Oncology Orthopaedics, Campus Bio-Medico University of Rome, Italy.
- 2010 – 2015: Resident program in Orthopaedic and Trauma Surgery, Vote: 50/50 cum laude, Campus Bio-Medico University of Rome, Italy.
- 2011- 2012: Clinical and research fellow at Centre of Sports and Exercise Medicine, Barts and the London, Queen Mary University of London, United Kingdom.
- 2003 – 2009: Degree of Medicine and Surgery, Vote: 110/110 summa cum laude, Campus Bio-Medico University of Rome, Italy
- 2008: Visiting research fellow at Orthopaedic Surgery Department Ferguson Laboratory for Spine Research, University of Pittsburgh, United States
Membership and Affiliations
- 2018: Visiting Fellowship of European Hip Society in The Netherlands
Awards and Honors
- 2022: Principal Investigator, call for proposals PRIN: Research projects of major National Interest, Prot. 2022YME9N3, title “Development and validation of an artificial intelligence algorithm based on clinical and radiographic data for the “virtual follow-up” of patients with total hip arthroplasty”. Funding agency: Italian Ministry of Health.
- 2021: Institutional Research Grant, Humanitas Research Hospital. Title: “Conventional versus mobile application-guided follow-up after joint replacement: a randomized controlled study.” Funding agency: IRCCS Humanitas Research Hospital.
- 2020: Institutional Research Grant, Italian Ministry of Health. Title: “Preoperative diagnosis of periprosthetic joint infection in patients undergoing total hip and knee arthroplasty revision: development and validation of a machine learning algorithm.” Funding agency: IRCCS Humanitas Research Hospital
- 2019: Co-Principal Investigator, Young Researcher Change Promoting, Ricerca Finalizzata. Title: “KneE microbiota in the phYsiopathology of oSteoarthritis. Microbes could play an imporTant rOle in a presumed Non-infectious disease (KEYSTONE).” Funding agency: Italian Ministry of Health.
- 2019: Institutional Research Grant, Italian Ministry of Health. Title: “Artificial intelligence for the “virtual follow-up” of patients with primary hip and knee arthroplasty: feasibility and efficacy study.” Funding agency: IRCCS Humanitas Research Hospital
- 2018: Best Presentation Award at 13th Congress of European Hip Society, The Hague, The Netherlands, “PTX3 as a new biomarker for the diagnosis of periprosthetic joint infection: a single-center pilot study”
- 2018: Principal Investigator, Young Researcher Change Promoting, Ricerca Finalizzata. Title: “Identification of early predictors of hip and knee arthroplasty failure by developing an innovative software for the automated analysis of radiographic examinations.” Funding agency: Italian Ministry of Health
- 2017: SIOT Level I Research Grant. Title: “Prospective observational study to assess the diagnostic ability of Long-Pentraxin 3 protein for the diagnosis of hip and knee periprosthetic joint infections.” Funding agency: SIOT (Italian Society of Orthopaedic and Traumatology)
- 2014: SIOT Level I Research Grant. Title: “Role of preoperative pelvic tilt in determining the range of motion and the rate of dislocation after primary total hip replacement.” Funding agency: SIOT (Italian Society of Orthopaedic and Traumatology)
- 2013: Recipient of the ISAKOS Achilles Orthopaedic Sports Medicine Research Award for the paper “Longo UG, Loppini M, Berton A, Marinozzi A, Maffulli N, Denaro V. The FIFA 11+ program is effective in preventing injuries in elite male basketball players: a cluster randomized controlled trial”
- 2013: Recipient of the Certificate Of Excellence in Reviewing by Foot and Ankle Surgery journal in cooperation with the European Foot and Ankle Society.
- Clinical and translational research to improve the current techniques and to develop innovative techniques in replacement and arthroscopic hip and knee surgery; to improve the outcome of patients undergoing hip and knee replacement surgery; to develop follow-up protocols based on artificial intelligence for patients with hip and knee replacement; to identify new biomarkers for the diagnosis of periprosthetic infections; to develop new diagnostic tools for periprosthetic infections with the application of machine learning algorithms; to develop protocols for rapid postoperative recovery (“fast track” in replacement surgery); to improve regenerative medicine strategies for degenerative diseases of hip and knee
- Author of 119 publications in international journals (Pubmed) and 19 other publications and book chapters. H-index Scopus: 34; Google Scholar: 44
- Member of Personalized Arthroplasty Society (PAS) – Education Committee and Corporate Development Committee since 2022
- Member of Education Committee (EduCom) of European Hip Society (EHS) since 2022
- Member of working groups of Network of Orthopaedic Registries of Europe (NORE, EFORT) since 2020
- Scientific Director – Fondazione Livio Sciutto Ricerca Biomedica in Ortopedia –ONLUS since 2018
- Editorial Board Member for International Journal of Orthopaedic since 2014
- Associate Editor for BMC Musculoskeletal Disorders since 2014
- Reviewer for Knee Surgery Sports Traumatology Arthroscopy Journal, BMC Musculoskeletal Disorders, Journal of Arthroplasty, Bone and Joint journal, International Orthopaedics, Hip International, International Journal Of Orthopaedic
- Loppini M, Di Maio M, Avigni R, Leone R, Inforzato A, Grappiolo G, Mantovani A, Bottazzi B. Long Pentraxin 3 as a New Biomarker for Diagnosis of Hip and Knee Periprosthetic Joint Infections. J Clin Med 2023 Jan 29;12(3):1055. doi: 10.3390/jcm12031055.
- Loppini M, Gambaro FM, Chiappetta K, Grappiolo G, Bianchi AM, Corino VDA. Automatic Identification of Failure in Hip Replacement: An Artificial Intelligence Approach. Bioengineering (Basel) 2022 Jun 29;9(7):288. doi: 10.3390/bioengineering9070288.
- Loppini M, Pisano A, Di Maio M, La Camera F, Casana M, Grappiolo G. (2021). Outcomes of patients with unexpected diagnosis of infection at total hip or total knee arthroplasty revisions. International orthopaedics, vol. 45, p. 2791-2796-2796, ISSN: 0341-2695, doi:10.1007/s00264-021-05137-8.
- Grappiolo G, La Camera F, Della Rocca A, Mazziotta G, Santoro G, Loppini M. Total hip arthroplasty with a monoblock conical stem and subtrochanteric transverse shortening osteotomy in Crowe type IV dysplastic hips. Int Orthop 2019 Jan;43(1):77-83. doi: 10.1007/s00264-018-4122-5. Epub 2018 Sep 5.
- Loppini M, Longo UG, Ragucci P, Trenti N, Balzarini L, Grappiolo G. Analysis of the Pelvic Functional Orientation in the Sagittal Plane: A Radiographic Study With EOS 2D/3D Technology. J Arthroplasty. 2017 Mar;32(3):1027-1032. doi: 10.1016/j.arth.2016.09.015. Epub 2016 Sep 28.