Sébastien Jaillon

Researcher Time Determined

General Pathology

E-mail sebastien.jaillon@hunimed.eu
Phone +39 0282245134

Biosketch

I got my PhD in immunology in 2007 (French Institute of Health and Medical Research (INSERM Unit-564, University of Angers, France). From January 2016 are “Assistant Professor” at Humanitas University, Milan, Italy. My activities research focuses on the cellular and molecular mechanisms involved in innate immunity and inflammation and its role in physiology and pathology (e.g. infections, cancer). my experience and leadership in the neutrophil biology, immunology, dell ‘ immunopathology and cancer can be marked by articles and reviews published in newspapers of the first band (e.g. Cell, Immunity, J Exp Med, Nat Rev Immunol, Blood).

Scientific and Research Interests

His scientific expertise reside primarily in morphological area :

  • optical microscopy,
  • electron microscopy,
  • histological preparations,
  • immunohistochemistry and immunofluorescence,
  • tracers of the nervous system.

Added to these are skills related to the management of laboratory animals, surgical preparation of animals for experimental studies on the nervous system, the electrophysiological techniques and primary and secondary cell cultures.

Main research areas today:

  1. Studies on the innate immune system with particular reference to the TLR receptors and ILR and pentraxine
  2. Studies on the development of the nervous system in conditions of activation of the maternal immune system

 

Most relevant publications

  • Occurrence and significance of tumor-associated neutrophils in patients with colorectal cancer. Galdiero MR, Smith P, Grizzi F, Di Caro G, Low G, Ponzetta A, E Bonavita, Barbagallo M, S Tartars, Polentarutti N, Malesci A, Marone G, Roncalli M, L Lakes, Garlanda C, Mantovani A, Jaillon S . Int J Cancer . 2016 March 3. doi: 10.1002 / ijc.30076. IF = 5
  • PTX3 is an extrinsic oncosuppressor regulating complement-dependent inflammation in cancer . Bonavita And, Dear S, M Rubino, Maina V, R Papait, Kunderfranco P, Greek C, F Feruglio, Molgora M, Laface I, Tartars S, Doni A, F Pasqualini, Barbati E, Low G, Galdiero MR, M Nebuloni Roncalli M, Colombo, P., Lakes, L., Lambris JD, Jaillon S , Garlanda C, Mantovani A. 2015 Feb; 160 (4): 700-14. IF = 32.2
  • The humoral pattern recognition molecule PTX3 is a key component of innate immunity against urinary tract infection. Jaillon S , F Moalli, Ragnarsdóttir B, Bonavita E, F Riva, Barbati And, Nebuloni M, Krajinovic LC , Markotic A, S Valentino, Doni A, Tartars S, G Graziani, Montanelli A, Delneste Y, Svanborg C, C Garlanda , Mantovani A. 2014 April; 40 (4): 621-32. IF = 21.5
  • Neutrophils in innate and adaptive immunity. Jaillon S , Galdiero MR, Del Prete D, Cassatella MA, Garlanda C, Mantovani A. Semin Immunopathol. 2013 Jul; 35 (4): 377-94. IF = 7.74
  • Neutrophils in the activation and regulation of innate and adaptive immunity. Mantovani A, Cassatella MA, Costantini C, Jaillon S . Nat Rev Immunol . 2011 Jul 25; 11 (8): 519-31. IF = 34.9
  • CCR7 is Involved in the migration of neutrophils to lymph nodes. Beauvillain C, P Cunin, Doni A, Scotet M, Jaillon S , ML Loiry, Magistrelli G, K Masternak, Chevailler A, Delneste Y, Jeannin P. Blood . 2011 Jan 27; 117 (4): 1196-204. IF = 10.4
  • The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps. Jaillon S , G Peri, Delneste Y, Frémaux I, Doni A, Moalli F, Garlanda C, L Romans, Gascan H, Bellocchio S, S Draft, Cassatella MA, P Jeannin, Mantovani A. J Exp Med. 2007 April 16; 204 (4): 793-804. IF = 12.5

Grants

2014

Grant “Gerry Scotti”, Humanitas Research Foundation

 

2012

Postdoctoral Investigator Award from the International Cytokine Society (Geneva, Switzerland. 11th-14th September 2012)

 

2012

Immunity Posters Prize (Training the innate immunity: immunological memory in innate host defense. Nijmegen, The Netherlands, June 28 & 29, 2012).

 

2010-2012

Bag FIRC (Italian Foundation for Cancer Research)

 

2008-2009

Bag Leem Recherche.

 

2004-2007

Bag Conseil General du Maine et Loire

Why
Humanitas
University?
An Established Institution

An Established Institution
Humanitas is a renowned healthcare institution that has offered Medical Degrees for well over a decade as a partner of the University of Milan.

An International Career

An International Career
Join our international medical community where classes are taught in English by experienced professors and medical doctors from around the world. Your degree will allow you to work as a MD in the EU and abroad.

Clinical Experience

Clinical Experience
Direct clinical experience is supported by a solid tutoring system and starts in your third year, which gives you considerable practical experience.

Innovative and Active Teaching

Innovative and Active Teaching
Humanitas curriculum is enhanced by a wide variety of active learning methods based on a student-centred approach (Problem-Based Learning, Case method, Concept maps, Simulated patients).

Milano and Italy

Milano and Italy
Enjoy the style, culture, gastronomy and entertainment of one of Europe's most exciting cities. Venture further to experience the delights of Italy or use the opportunity to learn Italian.

Advanced Research and Technology

Advanced Research and Technology
Humanitas can count on state-of-the-art technologies and research experience. A new simulation centre of 1000 sm, designed according to the highest technological standards, will be ready for autumn 2017.

Contact Us

Contact
Humanitas University
Via Rita Levi Montalcini 4,
Pieve Emanuele 20090 Milan, Italy

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Go straight on from Porta Ticinese, to Corso San Gottardo, to via Meda, via Montegani, and via dei Missaglia, then follow the signs for Istituto Clinico Humanitas, or Basiglio Milano 3.

By public transport

Go straight on from Porta Ticinese, to Corso San Gottardo, to via Meda, via Montegani, and via dei Missaglia, then follow the signs for Istituto Clinico Humanitas, or Basiglio Milano 3.