Gianluigi Condorelli

Full Professor
Cardiovascular Diseases

Head, Department of Cardiovascular Medicine, and Director of Cardiovascular Research at Humanitas Research Hospital  

Research Associate at the Institute of Genetics and Biomedical Research (IRGB), National Research Council of Italy.
Visiting Professor, Chair in Molecular Cardiology, University of Leicester, UK

Email gianluigi.condorelli@hunimed.eu
Site humanitas.net/doctors/condorelli-gianluigi

Biosketch

• 1999-2002 Assistant Professor, Department of Microbiology and Immunology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia
• 1999-06 Associate Professor, University La Sapienza, Rome
• 2003- Associate Research Scientist, Institute of Molecular Medicine, University of California San Diego, La Jolla CA
• 2006-09 Associate Professor, University of California San Diego, La Jolla, CA
• 2005-6 Scientific Director, Multimedica Research Hospital, Milan
• 2006-12 Head, Department of Medicine, National Research Council of Italy
• 2012-12 Acting Chair, Department of Biomedical Sciences, National Research Council of Italy
• 2008-12 Professor, University of Milan Bicocca
• 2009-13 Adjunct Professor of Medicine, University of California San Diego, La Jolla, CA
• 2012-15 Professor, University of Milan “Statale”
• 2015- Head, Department of Cardiovascular Medicine, and Director of Cardiovascular Research, Humanitas Research Hospital.

Scientific and Research Interests

“I have had a longstanding interest in the molecular mechanisms of cardiovascular diseases, in particular myocardial hypertrophy and failure and essential hypertension. A significant share of my research relates to the role of non-coding RNAs and epigenetics in regulating cardiovascular homeostasis and diseases. Other lines of research relate to monogenic cardiovascular diseases, in particular cardiomyopathies (genetics and iPSC models of diseases) and biomarkers of cardiovascular diseases in clinical pathophysiological conditions.”

 

Selected Publications

  1. Carè, A., Catalucci, D., Felicetti, F.,  Bonci,  D., Ruiz-Lozano, P.,  Gallo, P.,  Segnalini, P., Bang, M.L., Dorn, G.W.2nd,  Ellingsen, O., Croce, C.M., Peschle, C., and Condorelli G.(2007) – MicroRNA-133 controls cardiac myocyte hypertrophy. Nature Medicine, 13(5):613-8.

  2. Elia, L., Contu, R., Quitavalle, M., Varrone, F., Chimenti, C., Russo, M.A., Cimino, V., De Marinis, L.,, Frustaci, A., Catalucci, D., Condorelli, G.(2009) – Reciprocal regulation of microRNA-1 and IGF-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological conditions; Circulation, 120(23):2377-85.

  3. Elia, L. Quintavalle, M., Zhang, J., Contu, R., Cossu, L., Latronico, M.V.G., Peterson, K.L., Indolfi, C., Catalucci, D., Chen, J., Courtneidge. S.A., and Condorelli, G., (2009) – The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease. Cell Death and Diff. 16(12):1590-8

  4. Zhang, D.H., Latronico, M.V.G., Zhang, J.L., Contu, R., Rizzi, R., Catalucci, D., Peterson, K.L., Brown, J.H., Chen, J, Sonenberg, N. and Condorelli G. (2010) – mTORC-1 regulates cardiac function and myocyte survival through 4E-BP-1 inhibition. The Journal of Clinical Investigation, 120(8):2805-16

  5. Papait, R., Cattaneo, P., Kunderfranco, P., Greco, C., Carullo, P., Guffanti, A., Viganò, V., Stirparo, G.G., Latronico, M.V.G., Hasenfuss, G., Chen, J. and Condorelli, G., (2013) – Genome-wide analysis of histone marks identifying an epigenetic signature of promoters and enhancers underlying cardiac hypertrophy. PNAS USA, 110(50):20164-9

 

Academic Honors

  • P.I., National Institutes of Health, NHLBI, USA: Role of mTOR, a component of the AKT pathway, in regulating cardiac function (2011-15).
  • P.I. European Research Council Advanced Grant: Epigenetics and microRNAs in Myocardial Function and Disease (2012-17).
  • Supervisor, Marie Curie Outgoing Fellowship, recipient Paola Cattaneo, PhD (to UCSD).
  • Supervisor, Marie Curie Incoming Fellowship, recipient Michelle Monansky, PhD (from U. Illinois).
  • ERC Proof of Concept, PI.
Why
Humanitas
University?
An Established Institution

An Established Institution
Humanitas is a renowned healthcare institution that has offered Medical Degrees for well over a decade as a partner of the University of Milan.

An International Career

An International Career
Join our international medical community where classes are taught in English by experienced professors and medical doctors from around the world. Your degree will allow you to work as a MD in the EU and abroad.

Clinical Experience

Clinical Experience
Direct clinical experience is supported by a solid tutoring system and starts in your third year, which gives you considerable practical experience.

Innovative and Active Teaching

Innovative and Active Teaching
Humanitas curriculum is enhanced by a wide variety of active learning methods based on a student-centred approach (Problem-Based Learning, Case method, Concept maps, Simulated patients).

Milano and Italy

Milano and Italy
Enjoy the style, culture, gastronomy and entertainment of one of Europe's most exciting cities. Venture further to experience the delights of Italy or use the opportunity to learn Italian.

Advanced Research and Technology

Advanced Research and Technology
Humanitas can count on state-of-the-art technologies and research experience. A new simulation centre of 1000 sm, designed according to the highest technological standards, will be ready for autumn 2017.

Contact Us

Contact
Humanitas University
Via Rita Levi Montalcini 4,
Pieve Emanuele 20090 Milan, Italy

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