Gianluigi Condorelli

Full Professor of Cardiology MED/11

Head, Department of Cardiovascular Medicine, and Director of Cardiovascular Research at Humanitas Research Hospital 

Director Milan Unit, Institute of Genetics and Biomedical Research (IRGB), National Research Council of Italy.
Honorary Professor, Chair in Molecular Cardiology, University of Leicester, UK

Email gianluigi.condorelli@hunimed.eu

Phone + 390282244635

Site humanitas.net/doctors/condorelli-gianluigi

Biosketch

Dr. Gianluigi Condorelli is professor of cardiology, director of the post-graduate school of cardiology at Humanitas University, Milan, and head of the Department of Cardiovascular Medicine and of cardiovascular research at the Humanitas Research Hospital. He graduated cum laude in Medicine at the University “Federico II”, Naples, Italy, in 1989 and received a PhD in Cardiovascular Sciences from the University “Tor Vergata”, Rome, in 1993; he is a practicing cardiologist who trained in molecular cardiology at Harvard University, Boston, and in molecular oncology at Thomas Jefferson University, Philadelphia; he has been faculty at Thomas Jefferson University and at the University of California San Diego, La Jolla and director of the Department of Medicine, National Research Council of Italy. His research has been funded by grants from international agencies such the NHLBI-NIH USA, the European Union, the European Research Council (Advanced grant), the Fondation LeDucq and other relevant national ones.

Scientific and Research Interests

Dr Condorelli’s work focuses on the molecular mechanisms of cardiovascular diseases, in particular heart failure, studying the role of non-coding RNAs and epigenetics in this disease. Other lines of research are related to the understanding of the mechanisms of cardiomyopathies (by means of genetics and iPSCs), to the identification of biomarkers of cardiovascular diseases and, more recently, to the understanding of the role of innate and acquired immunity in cardiovascular diseases.

 

Selected Publications

  1. Condorelli, G., Drusco, A., Stassi, G., Roncarati, R., Iaccarino, G., Russo, M.A., Gu, Y., Chung, C., Latronico, M., Napoli, C., Sadoshima, J., Croce, C.M., and Ross, J., jr. (2002): Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice. Proc. Natl. Acad. Sci. USA, 99: 12333-8
  2. Carè, A., Catalucci, D., Felicetti, F., Bonci, D., Ruiz-Lozano, P., Gallo, P., Segnalini, P., Bang, M.L., Dorn, G.W.2nd, Ellingsen, O., Croce, C.M., Peschle, C., and Condorelli, G.(2007): MicroRNA-133 controls cardiac myocyte hypertrophy. Nature Medicine, 13(5):613-8.
  3. Zhang, D.H., Latronico, M.V.G., Zhang, J.L., Contu, R., Rizzi, R., Catalucci, D., Peterson, K.L., Brown, J.H., Chen, J, Sonenberg, N. and Condorelli G. (2010): mTORC-1 regulates cardiac function and myocyte survival through 4E-BP-1 inhibition. The Journal of Clinical Investigation, 120(8):2805-16
  4. Greco CM, Kunderfranco, P., Rubino, M., Larcher, V., Carullo, P., Anselmo, A., Kurz, K., Carell, T., Angius, A., Latronico, MiVG, Papait, R., and Condorelli G (2016) DNA Hydroxymethylation controls cardiomyocyte gene expression in development and hypertrophy Nature Comm, 7:12418. doi: 10.1038/ncomms12418
  5. Kallikourdis M, Martini E, Carullo P, Sardi C, Roselli G, Greco CM, Vignali D, Riva, F, Ormbostad Berre AM, Stolen TO, Fumero A, Faggian G, Di Pasquale E, Elia L, Rumio C, Catalucci D, Papait R, Condorelli G: T cell costimulation blockade blunts pressure overload-induced heart failure: Nature Comm, 8:14680

Academic Honors

  • P.I., National Institutes of Health, NHLBI, USA: Role of mTOR, a component of the AKT pathway, in regulating cardiac function (2011-15).
  • P.I. European Research Council Advanced Grant: Epigenetics and microRNAs in Myocardial Function and Disease (2012-17).
  • Supervisor, Marie Curie Outgoing Fellowship, recipient Paola Cattaneo, PhD (to UCSD).
  • Supervisor, Marie Curie Incoming Fellowship, recipient Michelle Monansky, PhD (from U. Illinois).
  • ERC Proof of Concept, PI.
Why
Humanitas
University?
An Established Institution

An Established Institution
Humanitas is a renowned healthcare institution that has offered Medical Degrees for well over a decade as a partner of the University of Milan.

An International Career

An International Career
Join our international medical community where classes are taught in English by experienced professors and medical doctors from around the world. Your degree will allow you to work as a MD in the EU and abroad.

Clinical Experience

Clinical Experience
Direct clinical experience is supported by a solid tutoring system and starts in your third year, which gives you considerable practical experience.

Innovative and Active Teaching

Innovative and Active Teaching
Humanitas curriculum is enhanced by a wide variety of active learning methods based on a student-centred approach (Problem-Based Learning, Case method, Concept maps, Simulated patients).

Milano and Italy

Milano and Italy
Enjoy the style, culture, gastronomy and entertainment of one of Europe's most exciting cities. Venture further to experience the delights of Italy or use the opportunity to learn Italian.

Advanced Research and Technology

Advanced Research and Technology
Humanitas can count on state-of-the-art technologies and research experience. The Campus includes also a simulation centre of 1000 sm, designed according to the highest technological standards.

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Contact
Humanitas University
Via Rita Levi Montalcini 4,
Pieve Emanuele 20090 Milan, Italy

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