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Massimo Roncalli

Professore Straordinario

Anatomia Patologica

Professore Straordinario

E-mail

massimo.roncalli@hunimed.eu
Telefono

+39 02 82244712

Full professor of Pathology, Hunimed University, 2015
University of Milan, 2003
Associate Professor of Pathology, University of Milan, 1992
PhD in Pathology, London University, 1995
Postgraduated in Forensic Medicine (1984) and Pathology (1981), University of Milan
Graduated summa cum laude (1978), University of Milan.

Translational investigation of human tumors with emphasis on those involving the GI tract and the liver.
Focus on mechanisms and phenotypic changes of hepatocarcinogenesis and on precursors of malignancy.
Discovery and validation of tissue biomarkers of diagnostic, prognostic and predictive significance.
Application of immunocytochemistry and molecular techniques to the characterization of human tumors.

Sciarra A, Di Tommaso L, Nakano M, Destro A, Torzilli G, Donadon M, Maggioni M, Bosari S, Bulfamante G, Matsuda M, Fujii H, Ichikawa T, Morisaka H, Sano K, Ichikawa S, Roncalli M. Morphophenotypic changes in human multistep hepatocarcinogenesis with translational implications. J Hepatol. 2016 Jan;64(1):87-93.
Sciarra A, Ronot M, Di Tommaso L, Raschioni C, Castera L, Belghiti J, Bedossa P, Vilgrain V, Roncalli M, Paradis V. TRIP: a pathological score for transarterial chemoembolization resistance individualized prediction in hepatocellular carcinoma. Liver Int. 2015 Nov;35(11):2466-73.
Vaira V, Roncalli M, Carnaghi C, Faversani A, Maggioni M, Augello C, Rimassa L, Pressiani T, Spagnuolo G, Di Tommaso L, Fagiuoli S, Rota Caremoli E, Barberis M, Labianca R, Santoro A, Bosari S. MicroRNA-425-3p predicts response to sorafenib therapy in patients with hepatocellular carcinoma. Liver Int. 2015 Mar;35(3):1077-86.
Nault JC, Calderaro J, Di Tommaso L, Balabaud C, Zafrani ES, Bioulac-Sage P, Roncalli M, Zucman-Rossi J. Telomerase reverse transcriptase promoter mutation is an early somatic genetic alteration in the transformation of premalignant nodules in hepatocellular carcinoma on cirrhosis. Hepatology. 2014 Dec;60(6):1983-92.
Perra A, Kowalik MA, Ghiso E, Ledda-Columbano GM, Di Tommaso L, Angioni MM, Raschioni C, Testore E, Roncalli M, Giordano S, Columbano A. YAP activation is an early event and a potential therapeutic target in liver cancer development. J Hepatol. 2014 Nov;61(5):1088-96.